2-thiosubstituted carbapenems

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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Details

549476, 549478, 544379, 546283, 548517, C07D30702

Patent

active

057507350

ABSTRACT:
Carbapenem antibiotic compounds of the general formula: ##STR1## wherein the moiety ##STR2## is a 4, 5 or 6 membered mono, di- or tri-substituted oxygen or sulfur containing ring; wherein Z is oxygen, sulfur, sulfoxide and sulfone, pharmaceutical compositions thereof useful for the treatment of bacterial infections, processes for preparing the compounds and new intermediates useful in the process.

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patent: 5321020 (1994-06-01), Jasys
CA62:9118d, Registry No. 89124-39-0, 1965.
CA92:128705, Van Den Bosch, 1975.
CA91:56820, Kahovcova, 1975.
CA108:38276, 1987.
L.T. Kaulinya and M.Y. Lidak, Khim. Geterotsikl. Soedin, 1, 94-99(1987) (translated).

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