2-thiosubstituted carbapenems

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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Details

540350, A61K 31395, A01N 4300, C07D48704

Patent

active

056021186

ABSTRACT:
Carbapenem antibiotic compounds of the general formula: ##STR1## wherein the moiety ##STR2## is a 4, 5 or 6 membered mono, di- or tri- substituted oxygen or sulfur containing ring; wherein Z is oxygen, sulfur, sulfoxide and sulfone, pharmaceutical compositions thereof useful for the treatment of bacterial infections, processes for preparing the compounds and new intermediates useful in the process.

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patent: 4477662 (1984-10-01), Corbett et al.
patent: 4745188 (1988-05-01), Christensen
patent: 4820817 (1989-04-01), Christensen
patent: 4997829 (1991-03-01), Ishiguro et al.
patent: 5102997 (1992-04-01), Sugimura et al.
patent: 5321020 (1994-06-01), Jasys

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