2-thiomethyl-substituted-pyridine and -3,5-dicarboxylates having

Details 2-thiomethyl-substituted-pyridine and -3,5-dicarboxylates having 2-thiomethyl-substituted-pyridine and -3,5-dicarboxylates having

1988-03-11

1990-04-17

Rotman, Alan L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546286, 546305, 546309, 546316, 546321, C07D21355, C07D21356, A61K 3144

Patent

active

049180878

ABSTRACT:
Pyridines of formula I ##STR1## wherein R.sub.1 is acetyl, benzoyl, cyano, nitro, alkoxycarbonyl or aminocarbonyl groups; R.sub.2 is an optionally substituted aryl or a heterocyclic group; and .phi. is a sulphurated residue such as alkylthio, cycloakylthio, arylthio, heteroarylthio, aminoalkylthio.
Compounds I are useful in therapy in cardiovascular field.

REFERENCES:
patent: 4845113 (1989-07-01), Gandolfi et al.

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