Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2003-05-16
2008-10-28
Shameem, Golam M (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C548S300100, C548S311100, C548S314700, C546S268100, C546S272700, C546S274100, C514S336000, C514S340000
Reexamination Certificate
active
07442713
ABSTRACT:
The invention relates to 2-thio-substituted imidazole derivatives of the formula Iin which the radicals R1, R2, R3, R4and p are as defined in the description. The compounds according to the invention have immunomodulating and/or cytokine-release-inhibiting action and are therefore suitable for treating disorders associated with a disturbed immune system.
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patent: 6432988 (2002-08-01), Laufer et al.
patent: 7253191 (2007-08-01), Laufer et al.
patent: 101 07 683 (2002-08-01), None
patent: WO 88/01167 (1988-02-01), None
patent: WO 99/03837 (1999-01-01), None
Laufer et al., “Towards the Improvement of the Synthesis of Novvel 4(5)-aryl-5(4)-heteroaryl-2-thio-substituted Imidazoles and Their p38 MAP Kinase Inhibitory Activity” J. Royal Soc. Chem. 6:437-439, 2008.
Albrecht Wolfgang
Laufer Stefan
Striegel Hans-Guenter
Tollmann Karola
Merckle GmbH
Rothwell Figg Ernst & Manbeck P.C.
Shameem Golam M
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