Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2007-08-07
2007-08-07
Shameem, Golam M. M. (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C546S268100, C546S272700, C546S274100, C514S336000, C514S385000, C514S397000, C514S398000
Reexamination Certificate
active
10467064
ABSTRACT:
The invention relates to 2-thio-substituted imidazole derivatives of the formula Iin which the radicals R1, R2, R3and R4are as defined in the description. The compounds according to the invention have immunomodulating and/or cytokine-release-inhibiting action and are therefore suitable for treating disorders associated with a disturbed immune system.
REFERENCES:
patent: 4190666 (1980-02-01), Cherkofsky et al.
patent: 4402960 (1983-09-01), Niedballa et al.
patent: 4461770 (1984-07-01), Ferrini et al.
patent: 4528298 (1985-07-01), Niedballa et al.
patent: 4584310 (1986-04-01), Ferrini et al.
patent: 4585771 (1986-04-01), Klose et al.
patent: 4608382 (1986-08-01), Ferrini et al.
patent: 5364875 (1994-11-01), Wilde
patent: 6040320 (2000-03-01), Beers et al.
patent: 6432988 (2002-08-01), Laufer et al.
patent: 2004/0116416 (2004-06-01), Laufer et al.
patent: 1083473 (1994-03-01), None
patent: 28 23 197 (1979-11-01), None
patent: 35 04 678 (1986-08-01), None
patent: 0 004 648 (1979-10-01), None
patent: 0 005 545 (1979-11-01), None
patent: 0 236 628 (1987-09-01), None
patent: 0 327 445 (1989-08-01), None
patent: 1 155 580 (1969-06-01), None
patent: 1 564 184 (1980-04-01), None
patent: 01 40467 (1989-02-01), None
patent: 91/10662 (1991-07-01), None
patent: 93 14081 (1993-07-01), None
patent: 95/00501 (1995-01-01), None
patent: WO 95/03297 (1995-02-01), None
patent: 96/03387 (1996-02-01), None
patent: 99 03837 (1999-01-01), None
patent: 00/17192 (2000-03-01), None
Ferrini et al (1980): STN International HCAPLUS database, Columbus (OH), accession No. 1980: 76510.
J. Med. Chem. vol. 39, pp. 3929-3937 1996.
Acta Chim. 61(1)69-77 1969(English Abstract Only).
Journal f.prakt. Chernie., Band 314, pp. 785-792 1972.
Grzegorz Mloston et al.: “Trapping of a thiocarbonyl ylide with imidazolethiones, pyrimidinethlone, and thioamides” Helvetica Chimica Acta., vol. 82, No. 2, pp. 290-296 1990.
Grzegorz Mloston et al.: “First examples of reactions of azole N-oxides with thioketones: a novel type of sulfur-transfer reaction” Helvetical Chimica Acta., vol. 81, No. 9, pp. 1585-1595, 1998.
Chemical Abstracts, vol. 117, No. 17, Oct. 26, 1992 abstract No. 166037b Beach, Dorothy C. et al.: “Inhibition of peroxidation by iron(III) and ascorbate”.
U.S. Appl. No. 10/524,486, filed Feb. 14, 2005, Laufer et al.
U.S. Appl. No. 10/524,839, filed Feb. 17, 2005, Laufer et al.
Kotschenreuther Dunja
Laufer Stefan
Merckle Philipp
Striegel Hans-Guenter
Tollmann Karola
Merckle GmbH
Oblon & Spivak, McClelland, Maier & Neustadt P.C.
Shameem Golam M. M.
LandOfFree
2-thio-substituted imidazole derivatives and the use thereof... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with 2-thio-substituted imidazole derivatives and the use thereof..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 2-thio-substituted imidazole derivatives and the use thereof... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3860558