2-thienylglycidic derivative, process for its preparation and it

Details 2-thienylglycidic derivative, process for its preparation and it 2-thienylglycidic derivative, process for its preparation and it

1991-07-02

1992-07-21

Dentz, Bernard

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546114, 549 75, C07D40704, C07D33322, C07D49504

Patent

active

051324350

ABSTRACT:
The invention relates to isopropyl 2-thienylglycidate of formula: ##STR1## obtained by reaction of 2-thienylcarboxaldehyde with an isopropyl haloacetate. It is employed as a synthesis intermediate in the preparation of 2-thienylacetaldoxime and of medications derived from thieno[3,2-c]pyridine.

REFERENCES:
Dullaghan et al., I, J. O. C., 17, pp. 1183-1186 (1952).
Dullaghan et al., II, J. O. C., 18, pp. 878-881 (1953).
Patent Abstracts of Japan, vol. 11, No. 317, (C-452) (2764), Oct. 15, 1987; & JP-A-62 103 087, (Toyo Pharma K.K.), May 15, 1987.
Chemical Abstracts of Japan, vol. 89, No. 3, Jul. 17, 1978, p. 650; & JP-A-53 07 687, (Sanwa Chemical Laboratories), Jan. 24, 1978.

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