2-t-butyl-3 alkyl-5-(m-hydroxyphenyl)-1,3-oxazolidines having my

Details 2-t-butyl-3 alkyl-5-(m-hydroxyphenyl)-1,3-oxazolidines having my 2-t-butyl-3 alkyl-5-(m-hydroxyphenyl)-1,3-oxazolidines having my

1987-11-06

1989-09-12

Shen, Cecilia

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

548215, A61K 3142, C07D49810

Patent

active

048660833

ABSTRACT:
An oxazolidine derivative of phenylephrine, and the non-toxic pharmaceutically acceptable salt forms thereof. The prodrug is much quicker absorbed across the cornea of the eye, does not induce the same unwanted side effects as phenylephrine, and can produce the same mydriatic effect as phenylephrine at dosage levels of approximately one-tenth the level of phenylephrine.

REFERENCES:
patent: 2243295 (1941-05-01), Susie et al.
patent: 4028368 (1977-06-01), Bodor et al.
patent: 4088783 (1978-05-01), Bodor et al.
patent: 4158005 (1979-06-01), Bodor et al.
patent: 4174450 (1979-11-01), Bodor et al.

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