2-Substituted thio-1,4-benzodiazepine derivatives

Details 2-Substituted thio-1,4-benzodiazepine derivatives 2-Substituted thio-1,4-benzodiazepine derivatives

1976-10-15

1978-06-13

Daus, Donald G.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260239B, 26029359, 26032681, 424244, 2602433, A61K 31395, C07D24322

Patent

active

040948706

ABSTRACT:
2-substituted thio-1,4-benzodiazepine derivatives having medicinal use of the general formula ##STR1## wherein R.sub.1 and R.sub.2 individually signify hydrogen atom or a halogen atom, or a nitro, amino, hydroxy, cyano, alkyl, haloalkyl, alkoxy, alkylthio, alkanesulfinyl, alkanesulfonyl, alkanoylamino or dialkylamino group, R.sub.3 signifies an alkylene group, and R.sub.4 and R.sub.5 individually signify hydrogen atom or an alkyl group and, when R.sub.4 and R.sub.5 are both alkyl groups, said alkyl groups together may form a ring with or without oxygen atom or an imino group, said ring optionally having a substituent or substituents, and its non-toxic pharmaceutically acceptable salts.

REFERENCES:
patent: 3481921 (1969-12-01), Field et al.
patent: 3856787 (1974-12-01), Steinman

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