2-(substituted sulfanyl)-3,5-dihydro-imidazol-4-one derivatives

Details 2-(substituted sulfanyl)-3,5-dihydro-imidazol-4-one derivatives 2-(substituted sulfanyl)-3,5-dihydro-imidazol-4-one derivatives

1995-11-28

1997-02-04

Jordan, Kimberly

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514824, A61K 31415

Patent

active

055998291

ABSTRACT:
A method for increasing blood serum HDL cholesterol levels in a mammal in need of increased HDL cholesterol blood serum levels, which comprises administering to said mammal, an effective amount of a compound of formula I: ##STR1## wherein R is phenyl or phenyl optionally substituted with one or more groups selected from halogen, alkyl, perfluoroalkyl, alkoxy, perfluoroalkoxy, hydroxy, alkanoyloxy, aroyloxy or arylalkanoyloxy; R.sup.3 is alkyl, aryl or arylalkyl; or a pharmaceutically acceptable salt thereof.

REFERENCES:
patent: 5137904 (1992-08-01), Baran et al.
patent: 5411981 (1995-05-01), Gaillard-Kelly et al.

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