2-(substituted sulfanyl)-3,5-dihydro-imidazol-4-one derivatives

Details 2-(substituted sulfanyl)-3,5-dihydro-imidazol-4-one derivatives 2-(substituted sulfanyl)-3,5-dihydro-imidazol-4-one derivatives

1996-11-21

1999-03-02

Morris, Patricia L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

5483195, 5483205, 5483211, C07D23386

Patent

active

058773240

ABSTRACT:
The compound of formula I: ##STR1## wherein R is phenyl or phenyl optionally substituted with one or more groups selected from halogen, alkyl, perfluoroalkyl, alkoxy, perfluoroalkoxy, hydroxy, alkanoyloxy, aroyloxy or arylalkanoyloxy; R.sup.3 is alkyl, aryl or arylalkyl; or a pharmaceutically acceptable salt thereof, are use for increasing HDL blood levels.

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patent: 5589497 (1996-12-01), Claussner et al.
Daboun et al, "Reactions of Amino Acids On 2-, Etc." CA 95:43024, 1981.
Scheiber, K.C., Chem Abst., vol. 49, No. 17, 11657h-11659a, Sep. 10, 1955.
Sauter et al., Heterocycles, 40(2) 851-866 (1995).
Harris et al., J. Med. Chem., vol. 35, 4384-4392 (1992).
Daboun, Z. Naturforsch., 866, 366-369 (1981).

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