2-substituted quinolines, and their use in medicaments

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514314, 514255, 514256, 546172, 546174, 546175, 544336, 544242, C07D40306, C07D21548, A61K 3147, A61K 31505

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active

053045637

ABSTRACT:
The title compounds are prepared either by reacting the corresponding halogenomethylquinolines with substituted phenols, optionally subsequently alkylating these or hydrolysing esters to acids, or by reacting phenyl-substituted quinolinecarboxylic acid derivatives with sulphonamides. The new phenyl-substituted quinolines are utilizable as active substances in medicaments, in particular as lipoxygenase inhibitors.

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