2-(substituted pyrrolidinylthio) carbapenem derivatives

Details 2-(substituted pyrrolidinylthio) carbapenem derivatives 2-(substituted pyrrolidinylthio) carbapenem derivatives

1992-09-25

1994-12-13

Richter, Johann

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

540350, A01N 4300, A61K 31395, C07D48704

Patent

active

053730020

ABSTRACT:
A compound of the formula: ##STR1## wherein R is a hydrogen atom or a methyl group, R.sup.1 is a hydrogen atom or a negative charge, R.sup.2 is a lower alkyl group, a lower alkyl group substituted with a hydroxyl group or --COOR.sup.3 (wherein R.sup.3 is a hydrogen atom or a lower alkyl group), A is .dbd.NH, .dbd.NR.sup.4 or .dbd.N(R.sup.4)R.sup.5 (wherein each of R.sup.4 and R.sup.5 which may be the same or different, is a lower alkyl group or a lower alkyl group substituted with a hydroxyl group), p is an integer of from 0 to 3, and each of q and r which may be the same or different, is an integer of from 0 to 5, provided that q and r are not simultaneously 0 and q +r.ltoreq.6; or a pharmaceutically acceptable salt or ester thereof.

REFERENCES:
patent: 4921852 (1990-05-01), Murata et al.
patent: 4925838 (1990-05-01), Murata et al.

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