2-(substituted piperazinylalkyl).beta.-carbolines useful in trea

Details 2-(substituted piperazinylalkyl).beta.-carbolines useful in trea 2-(substituted piperazinylalkyl).beta.-carbolines useful in trea

1985-09-16

1987-05-05

Daus, Donald G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

544298, 544319, 544320, 544328, 544331, 544333, 544334, 544357, 544361, 544375, 544396, C07D40314

Patent

active

046634568

ABSTRACT:
The .beta.-carbolines N-substituted in 2-position with a piperidinyl alkyl group are antipsychotic agents and anxiolytic agents with minimal extrapyramidal side effects, useful in the treatment of psychological disorders such as paranoia and schizophrania as well as general states of anxiety.

REFERENCES:
patent: 4427679 (1984-01-01), Welch et al.
patent: 4575508 (1986-03-01), Steiner et al.
Jilek et al., Chem. Abst. 54, 24798.
Koretskaya et al., Chem. Abst. 51, 15535.
Derwent Abstract 20,387 (Jap. 2713/66;2/21/66).

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