2-[(substituted)-phenoxymethyl]quinolines

Details 2-[(substituted)-phenoxymethyl]quinolines 2-[(substituted)-phenoxymethyl]quinolines

1985-06-18

1987-04-28

Rosen, Sam

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514312, 514313, 546152, 546153, 546155, 546156, 546159, A61K 3147, C07D21514

Patent

active

046614990

ABSTRACT:
Compounds having the formula: ##STR1## are selective antagonists of leukotrienes of D.sub.4 and inhibitors of the syntheses of LTA.sub.4, B.sub.4, C.sub.4, D.sub.4, E.sub.4, and F.sub.4. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory agents, and cytoprotective agents.

REFERENCES:
patent: 2727387 (1977-12-01), DEX
patent: 4236912 (1980-12-01), Johnston
patent: 4408076 (1983-10-01), Lee
patent: 4444584 (1984-04-01), Serban
J. Chem. Soc. Dalton 1259, 1264 (1980), Antony Deeming et al.
Org. Reactions, VII, R. Adams, ed., p. 82, (1953).
Aldrich Fine Chemicals, 58, 145 (1986).
Reagents for Org. Syn., 4, Fieser & Fieser, 448-449 (1974).

Affiliated with

Also associated with

Rating

2-[(substituted)-phenoxymethyl]quinolines does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 2-[(substituted)-phenoxymethyl]quinolines, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 2-[(substituted)-phenoxymethyl]quinolines will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-477533