2-Substituted or unsubstituted aminocarbonyloxyalkyl-1,4-dihydro

Details 2-Substituted or unsubstituted aminocarbonyloxyalkyl-1,4-dihydro 2-Substituted or unsubstituted aminocarbonyloxyalkyl-1,4-dihydro

1982-04-06

1983-09-13

Jiles, Henry R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Four or more ring nitrogens in the bicyclo ring system

544357, 544365, 546194, 546263, 546281, 546321, C07D41312, C07D21190

Patent

active

044043783

ABSTRACT:
Novel compounds having vasodilation and hypotensive effects are represented by the formula ##STR1## where R.sup.1 is halogen, nitro, cyano or lower alkoxy; each of R.sup.2 and R.sup.3 is lower alkyl, lower haloalkyl, lower alkoxyalkyl, aralkyloxyalkyl, aryloxyalkyl, lower alkenoxyalkyl, N,N-di-lower alkylaminoalkyl, N-lower alkyl-N-aralkylaminoalkyl, piperidylalkyl, 4-lower alkyl piperazinylalkyl, norpholinoalkyl or 1-pyrrolidinylalkyl; R.sup.4 is lower alkyl; A is lower alkylene; and R.sup.5 is hydrogen, lower alkyl, cycloalkyl of 3 to 7 carbon atoms, or aryl unsubstituted or substituted by one or two substituents selected from halogen, nitro, lower alkyl, lower alkoxy, di-lower alkylamino and cyano.
Also disclosed are processes for their preparation.

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