Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1991-08-13
1992-10-27
Shah, Mukund J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
544230, 544250, 544286, 558417, 558418, A61K 31505, C07D48704
Patent
active
051589532
ABSTRACT:
The present invention provides a novel series of 2-substituted methyl-2,3-dihydroimidazo[1,2-c]quinazolin-5(6H)-ones (-thiones) compounds. These compounds are found useful as an active ingredient for the prophylaxis and treatment of hypertension.
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Klein et al, Chemical Abstracts, vol. 110, No. 75431 (1989), (Abstract for Chem.-Ztg. 111, p. 373 (1989)).
Jun-ichi Imagawa, et al. Article entitled "Further Evaluation of the Selectivity of a Novel Antihypertensive Agent, SGB-1534, For Peripheral .alpha..sub.1 -Adrenoceptors in the Spinally Anesthetized Dog," Eur. J. Pharmacol., 131 257-264 (1986).
Imagawa et al., Chemical Abstracts, 106:43742t, (1987).
Chern Ji-Wang
Lu Guan-Yu
Shiau Chia-Yang
Yen Mao-Hsiung
Bernhardt F.
National Science Council
Shah Mukund J.
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