Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Cyclopentanohydrophenanthrene ring system doai
Reexamination Certificate
2004-02-19
2008-09-23
Badio, Barbara P (Department: 1612)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Cyclopentanohydrophenanthrene ring system doai
C552S531000, C552S610000, C552S614000, C552S626000
Reexamination Certificate
active
07427610
ABSTRACT:
Disclosed are compounds of formula Iand use thereof in a method of treating a tumor disease that can be influenced positively by the inhibition of tubulin polymerization.
REFERENCES:
patent: 6046186 (2000-04-01), Tanabe et al.
patent: 6339079 (2002-01-01), Kasch et al.
patent: 7071190 (2006-07-01), Goff et al.
patent: 2006/0211670 (2006-09-01), Hillisch et al.
patent: 19943708 (2001-03-01), None
patent: WO 98/42729 (1998-10-01), None
patent: WO 99/33858 (1999-07-01), None
patent: WO 0118028 (2001-03-01), None
MacCarthy-Morrogh L. et al: “Differential Effects of Estrone and Estrone-3-O-Sulfamate Derivatives on Mitotic Arrest, Apoptosis, and Microtubule Assembly in Human Breast Cancer Cells” Cancer Research, vol. 60, pp. 5441-5450, 2000.
Purohit A. et al: “Recent advances in the development of steroid sulphatase inhibitors” Journal of Steroid Biochemistry and Molecular Biology, Elsevier Science Ltd., vol. 69, (1999), pp. 227-238.
Singh A. et al.: “Inhibition of deoxyglucose uptake in MCF-7 breast cancer cells by 2-methoxyestrone and 2-methoxyestrone-3-O-sulfamate” Molecular and Cellular Endocrinology, vol. 160 (2000), pp. 61-66.
Bothe Ulrich
Gege Christian
Hillisch Alexander
Kosemund Dirk
Peters Olaf
Badio Barbara P
Millen White Zelano & Branigan P.C.
Sterix Limited
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