2-substituted carbonylimidazo[4,5-c]quinolines

Details 2-substituted carbonylimidazo[4,5-c]quinolines 2-substituted carbonylimidazo[4,5-c]quinolines

1989-02-14

1990-07-10

Lee, Mary C.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546 82, C07D47104, A61K 3147

Patent

active

049407147

ABSTRACT:
2-Substituted carbonylimidazo[4,5-c]quinolines of formula: ##STR1## having a high affinity for benzodiazepin receptor and showing an excellent psychostimulating action orally at a dose of 0.1-500 mg are provided through several routes.

REFERENCES:
patent: 4563463 (1986-01-01), Musser et al.
patent: 4689338 (1987-08-01), Gerster
patent: 4698348 (1987-10-01), Gerster
patent: 4753951 (1988-06-01), Takada et al.
Monatshefte fur Chemie 111(4), 963-969 (1980), Base Induced Cyclization of Some Quinolines, CA 94(7):47216f.
J. Wiley, The Chemistry of Functional Groups, Part II, 1970, pp. 201-287 Entitled "Biochemistry and Pharmacology of the Nitro and Nitroso Groups".

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