2-substituted benzimidazoles as selective androgen receptor...

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C514S394000, C548S310100

Reexamination Certificate

active

07932399

ABSTRACT:
The present invention is directed to a novel 2-substituted benzimidazole derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by the androgen receptor.

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Basaria, S. et al.: Anabolic-Androgenic Steroid Therapy in the Treatment of Chronic Diseases; The J. of Clin. Endocrinology & Metab (2001), 86(11), pp. 5108-5117.
Murphy, K.D. et al.: “Effects of long-term oxandrolone administration in severely burned children”, Surgery (2004), 136(2), pp. 219-224.
Newling, D.W.: Anti-androgens in the treatment of prostate cancer; Br. J. Urology (1996) 77(6), pp. 776-784.
Shahidi, N.T.: “A Review of the Chemistry, Biological Action, and Clinical Applications of Anabolic-Androgenic Steroids”, Clinical Therapeutics (2001) 23(9), pp. 1355-1390.
International Search Report and Written Opinion, PCT/US2007/060883, dated Jul. 2, 2007, 14 pages.

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