Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1977-12-02
1980-02-12
Randolph, John D.
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
424263, 424273R, C07D40102
Patent
active
041884868
ABSTRACT:
2-Substituted benzimidazole compounds of the formula: ##STR1## wherein R.sub.1 is hydrogen, halogen, lower alkyl or lower alkoxy, and R.sub.2 is hydrogen or lower alkyl with the proviso that R.sub.1 and R.sub.2 do not stand for hydrogen simultaneously and, when R.sub.1 is hydrogen, R.sub.2 cannot mean a methyl group at the 6th position on the pyridin-2-yl group or methyl an isobutyl group on the phenyl group; are useful as anti-inflammatory agents and/or analgesics.
REFERENCES:
Otaki et al., Yakugaku Zasshi, vol. 85, pp. 926 to 935, (1965).
Ridley et al., J. Heterocyclic Chem., vol. 2, pp. 453 to 456, (1965).
Osone et al., Chem. Abst., vol. 65, cols. 10577-10578, (1966).
Bachetti et al., Chem. Abst., vol. 52, cols. 15511-15512, (1958).
Farb. Bayer Akt.-Ges, Chem. Abst., vol. 53, col. 2256, (1959), (Abst. of Ger. No. 949,059).
C. H. Boehringer Sohn, Chem. Abst., vol. 53, col. 4317, (1959), (Abst. of Ger. No. 955,861).
Rao et al., Chem. Abst., vol. 51, cols. 8730-8731, (1957).
Ciba, Ltd., Chem. Abst., vol. 58, abst. of Brit. Pat. No. 901,648, col. 2455, (1963).
Brown et al., Chem. Abst., vol. 58, col. 2456 (abst. of U.S. Pat. No. 3,055,907) (1963).
Fara et al., Chem. Abst., vol. 65, col. 10984, (1966).
Ridi et al., Chem. Abst., vol. 70, abst. 87668r, (1969).
I.C.I., Chem. Abst., vol. 60, col. 15687 (abst. of Belg. No. 631,490).
Shiggo, Chem. Abst., vol. 69, abst. no. 36089z, (1968).
Balyaev et al., Chem. Abst., vol. 74, abst. no. 53650w, (1971).
Reddy et al., Chem. Abst. 72, abst. no. 31695w, (1970).
Hofmann, Imidazole and Its Derivatives, Part I, pp. 260 to 267, Interscience Publishers, Inc. New York, (1953).
Simonov et al., Chem. Abst., vol. 68, abst. no. 105088s, (1968).
Dezawa Katsumi
Ito Keiso
Kagaya Hajime
Kohno Toshihiko
Nose Takashi
Kanebo Ltd.
Randolph John D.
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