Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1996-08-08
1998-08-11
Dees, Jose G.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514326, 514327, 514330, 514333, 514347, 514352, 514354, 514427, 546184, 546193, 546208, 546216, 546223, 546244, 546248, 548518, 548530, 548541, 548564, A61K 3140, A61K 3144, A61K 31445, C07D207325, C07D21306, C07D21333, C07D29506, C07D40104
Patent
active
057927782
ABSTRACT:
The present invention addresses 2-substituted aryl pyrroles, as well as compositions containing such compounds and methods of treatment. Cytokine mediated diseases refers to diseases or conditions in which excessive or unregulated production or activity of one or more cytokines occurs. Interleukin-1 (IL-1), Interleukin-6 (IL-6), Interleukin-8 (IL-8) and Tumor Necrosis Factor (TNF) are cytokines which are involved.
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de Laszlo Stephen E.
Liverton Nigel J.
Mantlo Nathan B.
Ponticello Gerald S.
Selnick Harold G.
Daniel Mark R.
Dees Jos,e G.
Korsen Elliott
Merck & Co. , Inc.
Oswecki Jane C.
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