2-Substituted-5-oxo-5H-dibenzo-[A,D]cycloheptenes, the esters an

Details 2-Substituted-5-oxo-5H-dibenzo-[A,D]cycloheptenes, the esters an 2-Substituted-5-oxo-5H-dibenzo-[A,D]cycloheptenes, the esters an

1975-05-30

1976-06-29

Thomas, Jr., James O.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424331, 424298, 424299, 424311, 424308, 424285, 424283, 260468R, 260468G, 260469, 260478, 260485R, 260474, 2603478, 2603459, 260488CD, C07C 4976

Patent

active

039668207

ABSTRACT:
2-Substituted-5-oxo-5H-dibenzo [a,d]cycloheptenes represented by the following formula: ##SPC1##
Where one of R.sup.2 and R.sup.3 is hydrogen, and the other is hydrogen, methyl, or ethyl, or together R.sup.2 and R.sup.3 are methylene; the dotted line represents an optional, additional bond between the carbon atoms at the 10- and 11-positions; and the pharmaceutically acceptable esters and ethers thereof. The compounds have anti-inflammatory, analgesic, and antipyretic activities and, accordingly, are useful in the treatment of inflammation, pain and pyrexia.

REFERENCES:
patent: 3372192 (1968-03-01), Engelhardt
patent: 3478048 (1969-11-01), Edenhofer et al.
patent: 3551498 (1970-12-01), Tristram et al.
patent: 3697581 (1972-10-01), Humber
patent: 3833655 (1974-09-01), Edenhafer et al.
patent: 3836585 (1974-09-01), Tristram et al.
patent: 3883592 (1975-05-01), Bereyin et al.

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