Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1976-03-08
1977-07-26
Helfin, Bernard
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
260488CD, 260466, 260476C, 260468G, 260485L, 260473R, 260474, C07C 6902, C07C 6976
Patent
active
040382990
ABSTRACT:
2-Substituted-5-oxo-5H-dibenzo [a,d] cycloheptenes represented by the following formula: ##STR1## where one of R.sup.2 and R.sup.3 is hydrogen, and the other is hydrogen, methyl, or ethyl, or together R.sup.2 and R.sup.3 are methylene; the dotted line represents an optional, additional bond between the carbon atoms at the 10- and 11-positions; and the pharmaceutically acceptable esters and ethers thereof. The compounds have anti-inflammatory, analgesic, and antipyretic activities and, accordingly, are useful in the treatment of inflammation, pain and pyrexia.
REFERENCES:
patent: 3349093 (1967-10-01), van der Stelt
patent: 3819693 (1974-06-01), Levine et al.
patent: 3950425 (1976-04-01), VAN DER Burg
Nelson Peter H.
Untch Karl G.
Helfin Bernard
Krubiner Alan M.
Reamer James H.
Syntex (U.S.A.) Inc.
Walker William B.
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