2-substituted 5-oxazolyl indole compounds useful as IMPDH...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C548S235000, C548S236000, C549S049000

Reexamination Certificate

active

07008958

ABSTRACT:
Compounds having the formula (I),are effective as inhibitors of IMPDH enzyme, wherein R3is alkyl, substituted alkyl, alkoxy, haloalkoxy, or halogen, preferably methoxy, ethoxy, or trifluoromethoxy; and R1, R2, R4, and R5are as defined in the specification.

REFERENCES:
patent: 5317103 (1994-05-01), Baker et al.
patent: 5877329 (1999-03-01), Chen et al.
patent: 6353007 (2002-03-01), Sharma et al.
patent: 6492385 (2002-12-01), Myers et al.
patent: 438230 (1997-04-01), None
patent: WO 92/13856 (1992-08-01), None
patent: WO 97/21707 (1997-06-01), None
patent: WO 02/016333 (2002-02-01), None
Yang et al (1992): STN International CAPLUS database, Columbus, Ohio, Accession No., 1992:633770.
Quaedflieg et al., “An Alternative Route to the Preparation of (3′→5′) Methylene Acetal Linded Di- and Trinucleosides”,Synthesis, 1993, pp. 627-633.
Yang et al., “Synthesis of some 5-substituted indoles”,Heterocycles, vol. 34, pp. 1169-1175, 1992.
Zhang et al., “Synthesis of pyrimido[4,5-β]indoles and benzo[4,5]furo[2,3-α]pyrimidines via palladium-catalyzed intramolecular arylation”,Tetrahedron Letters, vol. 43, pp. 8235-8239, 2002.
Street et al., “Synthesis and Serotonergic Activity of 5-(Oxadiazoly)tryptamines: Potent Agonists for 5-HT1DReceptors”,J. Med. Chem., vol. 36, pp. 1529-1538, 1993.
Soares-Santos et al., “Blue-emitting fluorophores bases on 1,3-benzoxazolyl and 1,3-benzothiazolyl-substituted indoles and carbazoles”,Advances in Colour Science and Technology, vol. 5, pp. 94-98, 2002.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

2-substituted 5-oxazolyl indole compounds useful as IMPDH... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 2-substituted 5-oxazolyl indole compounds useful as IMPDH..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 2-substituted 5-oxazolyl indole compounds useful as IMPDH... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3578210

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.