2-substituted 4-(3-alkyl-5-tert.-butyl-4-hydroxyphenyl) thiazole

Details 2-substituted 4-(3-alkyl-5-tert.-butyl-4-hydroxyphenyl) thiazole 2-substituted 4-(3-alkyl-5-tert.-butyl-4-hydroxyphenyl) thiazole

1990-12-13

1992-08-11

Gerstl, Robert

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

548204, 548205, C07D27728, C07D27730, A61K 31425

Patent

active

051378973

ABSTRACT:
Novel substituted thiazoles of the formula I ##STR1## in which R.sup.1 is a saturated or unsaturated, straight-chain or branched C.sub.1 -C.sub.5 -alkyl group,

REFERENCES:
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Houben-Weyl, Meth. der. org. Chem., vol. IX, pp. 762-768 (1966).
Prof. Dr. W. Walter et al., Angew. Chem., vol. 78, No. 10, 1966, pp. 517-521 and 531-532.
Houben Weyl, vol. V/4, 1960, pp. 171-189.
L. C. King et al., J. of Org. Chem. vol. 29, 1964, pp. 3459-3461.
K. Inami et al., Bull. Chem. Soc. Jap., vol. 58, 1985, pp. 355-360.
R. J. Smith et al., Biochemical Pharmacology, vol. 37, No. 9, 1988, pp. 1667-1672.
K. U. Weithmann et al., Arzneim.-Forsch./Drug. Res., vol. 35(I), No. 6, 1985, pp. 947-952.

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