Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Allergen or component thereof
Patent
1977-11-28
1979-12-04
Randolph, John D.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Allergen or component thereof
424269, 548253, 549 26, 549 27, 2603452, A61K 3138, C07D49504
Patent
active
041772849
ABSTRACT:
Compounds of formula I ##STR1## in which R.sup.1 is hydrogen, halogen, nitro, trifluoromethyl, lower alkyl or lower alkoxy; R.sup.2 is hydrogen or lower alkyl; R.sup.3 is hydroxy, 1H-tetrazol-5-yl or COOR.sup.4 wherein R.sup.4 is hydrogen or lower alkyl, and X is O, S, SO or SO.sub.2, are disclosed. The compounds of formula I are useful for treating allergic conditions. Methods for the preparation and use of the compounds are disclosed.
REFERENCES:
patent: 3816467 (1974-06-01), Wright
patent: 3855216 (1974-12-01), Kaminsky et al.
patent: 3862144 (1975-01-01), Kaminsky
patent: 4060619 (1977-11-01), Philipp et al.
Dean et al., J. Chem. Soc., Chem. Comm., (1974), pp. 440-441.
Jirkovsky Ivo L.
Philipp Adolf H.
Ayerst McKenna & Harrison Ltd.
Randolph John D.
Wilfond Arthur E.
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