2-substituted-1-acyl-1,2-dihydroquinoline derivatives

Details 2-substituted-1-acyl-1,2-dihydroquinoline derivatives 2-substituted-1-acyl-1,2-dihydroquinoline derivatives

1998-01-29

1999-08-17

Huang, Evelyn Mei

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546168, 546169, A61K 3147, C07D21514

Patent

active

059394358

ABSTRACT:
This invention relates to the use of 2-substituted-1-acyl-1,2-dihydroquinoline derivatives to increase high density lipoprotein cholesterol (HDL-C) concentration and as therapeutic compositions for treating atherosclerotic conditions such as dyslipoproteinamias and coronary heart disease.

REFERENCES:
Walters, LR et al. J. Chem. Eng. Data 16(1), 115-17, 1971.
Popp and Soto, J. Chem. Soc. 1963, 1760-1763.
Popp, "Reissert Compounds and Related N-Acyldihydroquinolines," Quinolines, Part II, (1982), John Wilen & Sons, Ltd., pp. 353-375.
Cobb and McEwen, J. Amer. Chem. Soc., 77, 5042-5048 (1955).
Walters et al., J. Het. Chem. 5, 577-578, 1968.

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