2-substituted 1,8-dihydroxy-9(10H)-anthracenone pharmaceuticals

Details 2-substituted 1,8-dihydroxy-9(10H)-anthracenone pharmaceuticals 2-substituted 1,8-dihydroxy-9(10H)-anthracenone pharmaceuticals

1997-09-19

1999-07-13

Killos, Paul J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Polycyclo ring system containing anthracene configured ring...

514570, C07C 5016

Patent

active

059228911

ABSTRACT:
2-substituted 1,8-dihydroxy-9(10h)-anthracenones, therapeutic compositions containing at least one novel 2-substituted 1,8-dihydroxy-9(10h)-anthracenone compound and methods of treating inflammatory conditions are provided.

REFERENCES:
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Mueller, at al., Arch. Pharm. (Weinheim, Ger.), 320: 59-66 (1987).
Tranzer, et al., Arch. Pharm. (Weinheim, Ger.), 321: 447-449 (1988).
Mueller, et al., J. Med. Chem., 37: 1660-1669 (1994).
Finnen, M.J., Lancet II, 1129-1130 (1984).
Mueller, et al., Biochem. Pharmacol., 46: 1695-1704 (1993).
Corey et al, J. Am. Chem. Soc., 106: 1503-1504 (1984).
Takahashi, I et al, ChemPharm. Bull (1982) 30(12) 4539-44.
CA 116:50897 (1991).

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