Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1989-09-15
1991-09-24
Fan, Jane T.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
514255, 544370, 544392, 544393, A61K 31495, C07D40312
Patent
active
050514229
ABSTRACT:
This invention relates to novel 2-substituted-1(4)-aryl piperazines and to a process for their preparation. The compounds of this invention have been found to have cardiovascular, primarily antiarrhythmic effects and are of the following general formula I ##STR1## wherein R is hydrogen, lower alkyl or benzyl; and R.sub.1 and R.sub.2 are the same or independently hydrogen, lower alkyl, lower alkoxy or halogen;
REFERENCES:
patent: 4474783 (1984-10-01), Robba et al.
Farmaco Ed. Sci., 1984, E. Toja et al.
Lumma, Jr. William C.
Morgan, Jr. Thomas K.
Phillips Gary B.
Bellamy Elizabeth A.
Chang Celia
Fan Jane T.
Millen I. William
Schering AG
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