2-substituted 1,2-benzisothiazol-3(2H)-one 1,1-dioxide useful as

Details 2-substituted 1,2-benzisothiazol-3(2H)-one 1,1-dioxide useful as 2-substituted 1,2-benzisothiazol-3(2H)-one 1,1-dioxide useful as

1988-07-08

1989-08-22

Shen, Cecilia

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

544362, A61K 31495, C07D41714

Patent

active

048596710

ABSTRACT:
There is disclosed the compound 2-[4-[4-(2,7-naphthyridin-1-yl)-1-piperazinyl]butyl]-1,2-benzisothiazol-3( 2H)-one 1,1-dioxide, and the method of producing said compound, and the pharmaceutically acceptable salts thereof, and the use of said compound as an anxiolytic agent having a low liability for extrapyramidal side effects.

REFERENCES:
patent: 3717634 (1973-02-01), Wu et al.
patent: 4001223 (1977-01-01), Sugimoto
patent: 4202898 (1980-05-01), Depoortere
Fozard et al, British Journal of Pharmacology.

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