Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1993-08-19
1994-12-27
Lee, Mary C.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
514253, 514338, 544131, 544364, 546194, 546270, A61K 31425, C07D27504
Patent
active
053766539
ABSTRACT:
4-R.sup.4 -R.sup.5 -2-Saccharinylmethyl heterocyclic carboxylates, useful in the treatment of degenerative diseases, are prepared by reacting a 4-R.sup.4 -R.sup.5 -2-halomethylsaccharin with either a heterocyclic carboxylic acid in the presence of an acid-acceptor or the alkali metal salt of a heterocyclic carboxylic acid.
REFERENCES:
patent: 3002884 (1961-10-01), Lo
patent: 3314960 (1967-04-01), Freed et al.
patent: 4116964 (1978-09-01), Zinnes et al.
patent: 4195023 (1980-03-01), Mulvey et al.
patent: 4263393 (1981-04-01), Chen
patent: 4276298 (1981-06-01), Jones et al.
patent: 4350752 (1982-09-01), Reczek et al.
patent: 4363865 (1982-12-01), Reczek et al.
patent: 4410618 (1983-10-01), Vanmeter et al.
patent: 4547371 (1985-10-01), Doherty et al.
patent: 4623645 (1986-11-01), Doherty et al.
patent: 4659855 (1987-04-01), Powers
patent: 5128339 (1992-07-01), Dunlap et al.
Sunkel et al., J. Med. Chem. 31, 1886-1890 (1988).
Zimmerman et al., J. Biol. Chem. 225(20), 9848-9851 (1980).
Teshima et al., J. Biol. Chem., 257(9), 5085-5991 (1982).
Cha, Biochem. Pharmacol., 24, 2177-2185 (1975).
Powers et al., Biochem. 24, 2048-2058 (1985).
Svoboda et al., Coll. Czech. Chem. Commun., 51, 1133-1139 (1986).
Chiyomaru et al., Chemical Abstracts 81:22249n (1974).
Yoon et al., J. Korean Agricultural Chemical Society 1986, 29(2), 164-174.
Dunlap Richard P.
Latimer Lee H.
Subramanyam Chakrapani
Alexander Michael D.
DuPont Paul E.
Haley Jacqueline
Lee Mary C.
Sterling Winthrop Inc.
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