Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1995-05-19
1996-10-08
Richter, Johann
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
548210, 548455, 514414, 5142338, 514253, 514321, 546198, 544368, 544133, C07D27504, A61K 31425
Patent
active
055631630
ABSTRACT:
4-R.sup.4 -R.sup.5 -2-Saccharinylmethyl heterocyclic carboxylates, useful in the treatment of degenerative diseases, are prepared by reacting a 4-R.sup.4 -R.sup.5 -2-halomethylsaccharin with either a heterocyclic carboxylic acid in the presence of an acid-acceptor or the alkali metal salt of a heterocyclic carboxylic acid.
REFERENCES:
Sunkel et al., J. Med.Chem. (1988), 31, 1886-90.
Bell Malcolm R.
Court John J.
Desai Ranjit C.
Dunlap Richard P.
Hlasta Dennis J.
Cross Laura R.
DuPont Paul E.
Richter Johann
Sterling Winthrop Inc.
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