2-saccharinylmethyl aryl carboxylates useful as proteolytic enzy

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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548210, A61K 31425, C07D27506

Patent

active

055978410

ABSTRACT:
4-R.sup.4 -R.sup.5 -2-Saccharinylmethyl aryl carboxylates, useful in the treatment of degenerative diseases, are prepared by reacting a 4-R.sup.4 -R.sup.5 -2-halomethylsaccharin with an arylcarboxylic acid in the presence of an acid-acceptor.

REFERENCES:
patent: 4195023 (1980-03-01), Mulvey et al.
patent: 4276298 (1981-06-01), Jones et al.
patent: 4350752 (1982-09-01), Reczek et al.

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