Organic compounds -- part of the class 532-570 series – Organic compounds – Nitrogen attached directly or indirectly to the purine ring...
Patent
1986-06-24
1989-03-28
Rizzo, Nicholas S.
Organic compounds -- part of the class 532-570 series
Organic compounds
Nitrogen attached directly or indirectly to the purine ring...
544276, C07D47330, A61K 3152
Patent
active
048165751
ABSTRACT:
Neplanocin A derivatives of the formula ##STR1## wherein R.sub.1 is hydrogen or benzoyl, R.sub.4 is hydrogen or halogen, hydroxy, acetoxy, acetylthio, amino or azide, R.sub.5 is hydrogen or acetyl, and R.sub.6 is hydrogen or acetyl. The compounds of the present invention have inhibitory action for the growth of L 5178 Y cells and have the same or superior activity as neplanocin A.
REFERENCES:
patent: 4138562 (1979-02-01), Vince
patent: 4423218 (1983-12-01), Otani et al.
patent: 4613666 (1986-09-01), Fukikawa et al.
Fukukawa Kiyofumi
Hirano Takao
Tsujino Masatoshi
Ueda Tooru
Rizzo Nicholas S.
Toyo Jozo Kabushiki Kaisha
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