Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2005-02-22
2005-02-22
Seaman, D. Margaret (Department: 1625)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S292000, C514S293000, C546S080000, C546S081000, C546S082000, C546S083000, C546S084000
Reexamination Certificate
active
06858621
ABSTRACT:
The present invention is directed to novel 2-(quinolonyl)-fused heterocyclyl derivatives of the general formula (I)wherein R1, R2, R3, R3a, R4, R5, R6and R7are as herein defined, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by the androgen receptor.
REFERENCES:
patent: 5677336 (1997-10-01), Jones et al.
patent: 5696130 (1997-12-01), Jones et al.
patent: 5716983 (1998-02-01), Friebe et al.
patent: 6017924 (2000-01-01), Edwards et al.
patent: 3120283 (1991-05-01), None
patent: WO 9502588 (1995-01-01), None
patent: WO 9511215 (1995-04-01), None
patent: WO 9749709 (1997-12-01), None
patent: WO 9931086 (1999-06-01), None
patent: WO 0116139 (2001-03-01), None
patent: WO 02066475 (2002-08-01), None
patent: WO 02068427 (2002-09-01), None
Shanazarov, Chemical Abstracts 115:114416, abstract of Khimiya Geterotsiklicheskikh soedinenii, 1991, vol. (1), pp 86-92.*
Sharma, Chemical abstracts 96:6657, abstract of Indian Journal of Chemistry, Secition B, 1981, vol. 20B(9), 744-746.*
Sharma, chemical abstracts 106:84499, abstract of indian journal of chemistry, section b, 1986, vol. 25B(3), pp 271-274.*
Basaria, S. et al.: “Anabolic-Androgenic Steroid Therapy in the Treatment of Chronic Diseases”; The J. of Clin. Endocrinology & Metabolism (2001) 86(11), pp. 5108-5117.
Bashir, M. et al.: “Biological Formation and Chemical Synthesis of 2-Amino-3,6-Dihydro-3-Methyl-7H-Imidazolo[4,5-f]Quinolin-7-One, the Major Metabolite of the Dietary Carcinogen 2-Amino-3-Methyl-3H-Imidazolo[4,5-f]Quinoline (IQ) by Normal Intestinal Bacteria”; Heterocycles, 1987, vol. 26, No. 11, pp. 2877-2886.
Newling, D.W.W.; “Anti-androgens in the treatment of prostate cancer”; British J. of Urology, 1996, 77, pp. 776-784.
Shahidi, N.T.: “A Review of the Chemistry, Biological Action, and Clinical Applications of Anabolic-Androgenic steroids”; Clin. Therapeutics, 2001, vol. 23, No. 9, pp. 1355-1390.
Uray, G. et al.: “Long-Wavelenth-Absorbing and -Emitting Carbostyrils with High Fluorescence Quantum Yields”; Helvetica Chimica Acta, vol. 82 (1999), pp. 1408-1417.
Fiordeliso James J.
Lanter James C.
Sui Zhihua
Ortho-McNeil Pharmaceutical , Inc.
Seaman D. Margaret
LandOfFree
2-(quinolonyl)-fused heterocycles as androgen receptor... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with 2-(quinolonyl)-fused heterocycles as androgen receptor..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 2-(quinolonyl)-fused heterocycles as androgen receptor... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3473299