2-Quantum selective MR sequence for selectively determining a nu

Electricity: measuring and testing – Particle precession resonance – Using a nuclear resonance spectrometer system

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G01R 3320

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active

050814176

ABSTRACT:
A 2-quantum selective MR sequence is proposed for the selective determination of the nuclear magnetisation distribution of a metabolite such as lacate while suppressing at the same time another metabolite such as alanine. A 2-quantum selective sequence which contains three 90.degree. pulses (p1, p2, p3) and two gradients (G1r, G2r) for the selection of 2-quantum coherence is performed twice, the polarity of one of the two gradients (G1r, G1r') being reversed. When the time interval (tb) between the second (p2) and the third (p3) pulse is suitably chosen, a spectrum of a metabolite such as lactate is selectively determined from the amplitude modulated sum signal of the resonance signals generated by the sequence.

REFERENCES:
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patent: 4843321 (1989-06-01), Sotak
patent: 4962357 (1990-10-01), Sotak
Chemical Physics Letters, 1 Feb. 1980, pp. 567-570, by A. Bax et al, "Separation of the Different Orders of NMR Multiple-Quantum Transitions by the use of Pulse Field Gradients".

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