2-pyrrolyl-cycloalkyl-amide analgesics

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514409, 548407, 548565, A61K 3140, C07D20720

Patent

active

045980888

ABSTRACT:
N-[2-(2,5-dihydro-1H-pyrrol-1-yl)cycloaliphatic)]benzeneacetamide and -benzamide compounds, e.g., (1.alpha.,2.beta.)-(.+-.)-3,4-dichloro-N-[2-(2,5-dihydro-1H-pyrrol-1-yl)cy clohexyl]-N-methylbenzeneacetamide, and salts thereof, have useful analgesic activity, low abuse or physical dependence liability properties. Processes for their preparation are disclosed. Pharmaceutical compositions containing such compounds and methods for their use are also disclosed.

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patent: 4438130 (1984-03-01), Kaplan
patent: 4460600 (1984-07-01), Kaplan et al.
patent: 4466977 (1984-08-01), McMillan et al.

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