2-pyrimidinyl-1-piperazine derivatives, processes for their prep

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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514241, 514253, 5142342, 5142352, 5142338, 5142345, 544 12, 544 49, 544 94, 544116, 544121, 544231, 544284, 544285, 544295, 548123, 548210, A61K 3154, C07D41714

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048187569

ABSTRACT:
The invention relates to substituted 2-pyrimidinyl-1-piperazine derivatives defined herein by formula (I), processes for their manufacture, compositions containing said substituted 2-pyrimidinyl-1-piperazine derivatives as active materials and the use of said compounds and compositions as agents effecting the central nervous system. Also included in the invention are intermediates of formula (VIII) for making the active formula (I) compounds.

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patent: 4507303 (1985-03-01), Ishizumi et al.
patent: 4524206 (1985-06-01), New et al.
patent: 4543355 (1985-09-01), Ishizumi et al.
patent: 4732984 (1988-03-01), Abou-Gharbia et al.
Hirose et al., "Chemical Abstracts", vol. 98, 1983, col. 98:126160u.
"Chemical Abstracts", vol. 101, 1984, col. 101:110951x.
Traber et al., "Chemical Abstracts", vol. 101, 1984, col. 101:204160r.

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