2-Pyridyl-2-thiazoline-4-carboxylic acid derivatives

Details 2-Pyridyl-2-thiazoline-4-carboxylic acid derivatives 2-Pyridyl-2-thiazoline-4-carboxylic acid derivatives

1981-07-23

1983-09-27

Fan, Jane T.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

546280, 435120, A61K 3144, C07D40904

Patent

active

044069057

ABSTRACT:
The invention relates especially to 2-(3'-hydroxypyrid-2'-yl)-2-thiazoline-4-carboxylic acid derivatives of the formula (I) and salts and also certain metal complexes of these compounds, processes for their manufacture, pharmaceutical agents containing such compounds and the use of these compounds. ##STR1## In the formula, R.sup.1 represents free, etherified or esterified hydroxy, R.sup.2 represents hydrogen or an aliphatic, carbocyclic or carbocyclic-aliphatic radical having 1-12 carbon atoms, and R.sup.3 represents hydrogen or an unsubstituted aliphatic radical having 1-7 carbon atoms.
The compounds of the formula (I) can be used, for example, for the abstraction of heavy metals from the organism of warm-blooded animals and/or they have an antibiotic action.

REFERENCES:
patent: 3592905 (1971-07-01), Shen et al.
patent: 3842172 (1974-10-01), Arlyan et al.
patent: 3852293 (1974-12-01), Arlyan et al.
patent: 4260765 (1981-04-01), Harrison et al.
H. U. Naegeli and H. Zahner, Helv. Chim. Acta 63:6, 1400-1406.
I. Steffan and B. Prijs, Helv. Chim. Acta XLIV:V, 1429-1432.

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