Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1982-11-18
1984-02-14
Bond, Robert T.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
546257, 546301, A61K 3144, C07D21356
Patent
active
044316518
ABSTRACT:
3,4-Dihydro-3-R.sub.1 -4-R.sub.2 -5-Q-6-R-2(1H)-pyridinones (I), where R.sub.1 and R.sub.2 are each hydrogen or methyl, R is lower-alkyl, and Q is 4(or 3)-hydroxyphenyl, 4(or 3)-methoxyphenyl, 4(or 3)-pyridinyl or 4(or 3)-pyridinyl having one or two lower-alkyl substituents, or acid-addition salts thereof, and their preparation are shown. Also shown is the cardiotonic use of I where Q is 4(or 3)-hydroxyphenyl, 4(or 3)-pyridinyl or 4(or 3)-pyridinyl having one or two lower-alkyl substituents.
REFERENCES:
patent: 3718743 (1973-02-01), Shen et al.
patent: 4004012 (1977-01-01), Lesher et al.
patent: 4072746 (1978-02-01), Lesher et al.
patent: 4312875 (1982-01-01), Lesher et al.
Carabateas Philip M.
Lesher George Y.
Singh Baldev
Bair Robert K.
Bond Robert T.
DuPont Paul E.
Sterling Drug Inc.
Wyatt B. Woodrow
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