2-(pyridin-2-ylamino)-pyrido[2,3, d]pyrimidin-7-ones

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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Details

C514S218000, C514S234200, C514S252160, C514S264110, C540S575000, C540S600000, C544S117000, C544S279000

Reexamination Certificate

active

07456168

ABSTRACT:
The present invention provides substituted 2-aminopyridines useful in treating cell proliferative disorders. The novel compounds of the present invention are potent inhibitors of cyclin-dependent kinases 4 (cdk4).

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Blain, S., et al., “Differential Interaction Of The Cyclin-Dependent Kinase (Cdk) Inhibitor,”The Journal Of Biological Chemistry, 1997, 25863-25872, vol. 272, No. 41.
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