2-(Pyrid-2-yl)tetrahydrothiophene derivatives

Details 2-(Pyrid-2-yl)tetrahydrothiophene derivatives 2-(Pyrid-2-yl)tetrahydrothiophene derivatives

1980-03-26

1981-06-09

Rotman, Alan L.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

424250, 424263, 424267, 544131, 544360, 546193, 546284, A61K 3144, A61K 31495, C07D41314

Patent

active

042725348

ABSTRACT:
Compounds of the formula: ##STR1## wherein R represents hydrogen or alkyl of 1 through 4 carbon atoms, and R.sub.1 and R.sub.2 represent hydrogen or alkyl of 1 through 15 carbon atoms, or alkyl of 1 through 15 carbon atoms substituted by one substituent selected from (i) hydroxy, (ii) alkylamino in which the alkyl radical is of 1 through 4 carbon atoms, (iii) dialkylamino in which the alkyl radicals are of 1 through 4 carbon atoms, (iv) phenyl, (v) carboxy, and (vi) alkoxycarbonyl in which the alkoxy radical is of 1 through 4 carbon atoms, or R.sub.1 and R.sub.2 together with the nitrogen atom to which they are attached represent a five- or six-membered heterocyclic radical, are new compounds. They possess pharmacological properties and are particularly useful in the treatment of gastro-intestinal ulcers.

REFERENCES:
patent: 3740409 (1973-06-01), Brenner et al.
patent: 3873536 (1975-03-01), Caldwell et al.
patent: 3898228 (1975-08-01), Loev
patent: 3917593 (1975-11-01), Loev

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