Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1981-03-20
1982-09-28
Coughlan, Jr., Paul M.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
2602433, 424251, 544284, 544291, 544295, C07D40314, C07D41714, C07D49804
Patent
active
043518320
ABSTRACT:
Herein is disclosed 2-(1-piperazinyl)-4-pyrimidinamine derivatives, acid addition salts thereof, processes for their preparation, methods of using the derivatives and pharmaceutical compositions of the derivatives. The derivatives are distinguished most readily by having novel substituents at position 4 of the piperazinyl radical, the substituents being selected from the group consisting of 2-thiazoylyl, oxazolo(4,5-b)pyridin-2-yl and optionally substituted 1-(lower alkyl)-1H-benzimidazol-2-yl. The derivatives are useful for treating hypertension in a mammal.
REFERENCES:
patent: 3511836 (1970-05-01), Hess
patent: 3935213 (1976-01-01), Hess
patent: 4001237 (1977-01-01), Partyka et al.
patent: 4093726 (1978-06-01), Winn et al.
patent: 4287341 (1981-09-01), Hess et al.
Al Thuis et al., J. Med. Chem., 20, 146-149, (1977).
Derwent Publications Ltd., Farm Doc. 36461B for Netherland, Patent 7,804,135.
Bagli Jehan F.
Rakhit Sumanas
American Home Products Corporation
Coughlan, Jr. Paul M.
Wilfond Arthur E.
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