Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2005-08-26
2010-10-26
Landau, Sharmila Gollamudi (Department: 1611)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C546S326000
Reexamination Certificate
active
07820700
ABSTRACT:
The present invention relates to a novel 2-phenylpyridine derivative or a salt thereof, wherein the pyridine ring is substituted with a carboxyl group or the like and the benzene ring has an electron-withdrawing group such as a cyano group and an electron-donating group such as a substituted alkoxy group at the same time.Since the compound of the invention has good xanthine oxidase-inhibitory action and uric acid-lowering action and does not have a structure derived from nucleic acid, the compound has advantages of high safety and excellent effects as compared with conventional compounds and is useful as a therapeutic or preventive agent for hyperuricemia, gout, inflammatory bowel diseases, diabetic kidney diseases, diabetic retinopathy, or the like.
REFERENCES:
patent: 3655679 (1972-04-01), Tsung-Ying et al.
patent: 3703582 (1972-11-01), Tsung-Ying et al.
patent: 4346094 (1982-08-01), Beck et al.
patent: 4495195 (1985-01-01), Beck et al.
patent: 4544752 (1985-10-01), Beck et al.
patent: 5614520 (1997-03-01), Kondo et al.
patent: 5843969 (1998-12-01), Ota et al.
patent: 6015829 (2000-01-01), Ishibuchi et al.
patent: 6395753 (2002-05-01), Kodama et al.
patent: 57-85379 (1982-05-01), None
patent: 59-095272 (1984-06-01), None
patent: 06-065210 (1994-03-01), None
patent: 06-211815 (1994-08-01), None
patent: 10-310578 (1998-11-01), None
patent: 2000-001431 (2000-01-01), None
patent: 2002-105067 (2002-04-01), None
patent: WO 92/09279 (1992-06-01), None
patent: WO 96/31211 (1996-10-01), None
patent: WO 98/18765 (1998-05-01), None
patent: WO 02/098840 (2002-12-01), None
patent: WO 03/020703 (2003-03-01), None
Cuisa et al. Influence of various pyridine derivatives on the elimination of uric acid, Annali di Chimica Applicate, 1931, vol. 21, p. 553-8, Chemical Abstract No. 26: 28808.
Walford et al. Ant inflammatory Analogs of Flufenisal, Journal of Medicinal Chemistry, 1971, col. 14, No. 4, p. 339-344.
Asano Toru
Kawakami Masakatsu
Miyata Junji
Naito Ryo
Astellas Pharma Inc.
Klinkel Kortney L
Landau Sharmila Gollamudi
Sughrue & Mion, PLLC
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