2-phenylpyrazolo[1,5-a]pyrimidine-3-acetic acid derivatives exhi

Details 2-phenylpyrazolo[1,5-a]pyrimidine-3-acetic acid derivatives exhi 2-phenylpyrazolo[1,5-a]pyrimidine-3-acetic acid derivatives exhi

1991-04-12

1992-05-19

Berch, Mark L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

544281, 548375, 548377, C07D48704, A61K 31505

Patent

active

051149443

ABSTRACT:
This invention provides a 2-arylpyrazolo[1,5-a]pyrimidine-3-acetic acid corresponding to the formula: ##STR1## where X is hydrogen or a halogen, hydroxy, C.sub.1 -C.sub.4 alkyl or C.sub.1 -C.sub.4 alkoxy substituent; Y is hydrogen or a halogen, C.sub.1 -C.sub.4 alkyl or C.sub.1 -C.sub.4 alkoxy substituent; Z is a hydroxy, C.sub.1 -C.sub.4 alkoxy or --NRR substituent; and R is hydrogen or a C.sub.1 -C.sub.4 alkyl substituent; or a pharmaceutically acceptable salt thereof which is useful as a therapeutic agent which exhibits anxiolytic, anticonvulsant and muscle relaxant effects in a warm blooded animal.

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