Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1984-02-08
1988-02-23
Moyer, Donald B.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514554, 514640, 564256, 26050117, A61K 31495, A61K 3115, A61K 31205, C07C13102
Patent
active
047270748
ABSTRACT:
The invention relates to selected stereoisomers having the E, E or E, Z configuration and within the Formula (I) ##STR1## wherein N is 2-4, A is alkylene or 2 or 3 carbon atoms, R is phenyl or substituted phenyl and R.sup.1 and R.sup.2 are lower alkyl, or, together with the carbon to which attached, form a heterocyclic ring; and pharmaceutically acceptable acid addition salts thereof, a process for their preparation and pharmaceutical compositions comprising the same.
The compounds of the general formula (I) can be used in therapy due to their narcosis potentiating, analgesic and antiarrhythmial effect.
REFERENCES:
patent: 4077999 (1978-03-01), Budai et al.
Newbould, B. B. et al. Br. J. Pharmac. vol. 35 (1969) pp. 487-497.
Kuhn, W. L. et al. J. Pharm. Exptl. Ther. vol. 134 (1961) pp. 60-68.
Marmo, E. et al. Arzneimittelforschung vol. 20 (1970) pp. 1-18.
Litchfield, J. T. et al. J. Pharmacol. Exp. Ther. vol. 96 (1949) pp. 99-113.
Marmo, Von E. et al. Arzneimittel-Forschung vol. 20 (1970) pp. 3-18.
Rudiger, Heinz Jurgen et al. Naunym-Schmiedeberg's Arch Pharmacol (1981) vol. 317 pp. 238-244.
Budai Zoltan
Grasser Katalin
Lay nee Konya Aranka
Mezei Tibor
Petocz Lujza
Egyt Gyogyszervegyeszeti Gyar
Hendriksen L.
Moyer Donald B.
LandOfFree
2-(phenylmethylene)-1-(diaminoalkoxy) cycloalkanes and their pha does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with 2-(phenylmethylene)-1-(diaminoalkoxy) cycloalkanes and their pha, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 2-(phenylmethylene)-1-(diaminoalkoxy) cycloalkanes and their pha will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-603032