Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Parasitic organism or component thereof or substance...
Patent
1979-02-12
1980-07-22
Trousof, Natalie
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Parasitic organism or component thereof or substance...
548315, A61K 31415, C07D23350
Patent
active
042139953
ABSTRACT:
Compounds of the formula ##STR1## wherein R is 2,6-dichloro-4-hydroxymethyl-phenyl; 2-chloro-4-methyl-5-amino-phenyl; 2,5-dichloro-4-methyl-phenyl; 2-chloro-4-methyl-5-nitro-phenyl; 2,3-dichloro-4-methyl-phenyl; 2-chloro-4-methyl-6-nitro-phenyl; 2-chloro-4-methyl-6-amino-phenyl; 2,4,6-trifluorophenyl; tetrafluoro-phenyl; or 3-bromo-4-fluoro-phenyl; and non-toxic, pharmacologically acceptable acid addition salts thereof. The compounds as well as their salts are useful as hypotensives.
REFERENCES:
patent: 3236857 (1966-02-01), Zeile et al.
patent: 3468887 (1969-09-01), Stahle et al.
patent: 3595961 (1971-07-01), Stahle et al.
patent: 4025607 (1977-05-01), Stahle et al.
Hoefke Wolfgang
Koppe Herbert
Kummer Werner
Pichler Ludwig
Stahle Helmut
Boehringer Ingelheim GmbH
Trousof Natalie
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