2-phenylhexahydro-1,2,4-triazine-3-,5-diones

Details 2-phenylhexahydro-1,2,4-triazine-3-,5-diones 2-phenylhexahydro-1,2,4-triazine-3-,5-diones

1986-09-05

1988-11-01

Ford, John M.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

544182, 544112, 544 585, 544 83, 5142278, 5142362, A61K 3153, C07D25306

Patent

active

047820560

ABSTRACT:
Compounds of the formula I ##STR1## with n=1-3, R=H, Hal, CF.sub.3, alkyl, cycloalkyl, alkyloxy, alkylthio, alkylsulfinyl, alkylsulfonyl, benzylsulfinyl, benzylsulfonyl, nitro, cyano, amino, alkylamino, dialkylamino, piperidino, morpholino, pyrrolidinyl, 4-methyl-1-piperazinyl, acylamino or substituted phenoxy, phenylthio, phenylsulfinyl, phenylsulfonyl, benzoyl, benzoylamino or anilino, with R.sup.2 =H, alkyl, cycloalkyl, optionally substituted benzyl, alkanoyl or benzoyl and R.sup.3 =H, alkyl, cycloalkyl or optionally substituted benzyl, at least R.sup.2 or R.sup.3 not being H, are obtained by alkylation or acylation of a compound II ##STR2## in which R.sup.1 is as defined above, with compounds R.sup.3 X (X=leaving group) or R.sup.2 Y (Y=leaving group), R.sup.2 and R.sup.3 being defined as indicated.
Compounds I are coccidiostatics.

REFERENCES:
patent: 4198407 (1980-04-01), Rosner et al.
patent: 4426522 (1984-01-01), Simonovitch
patent: 4640917 (1987-02-01), Rosner et al.

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