2-Phenylbenzofuran derivatives, a process for preparing...

Details 2-Phenylbenzofuran derivatives, a process for preparing... 2-Phenylbenzofuran derivatives, a process for preparing...

2006-12-12

2006-12-12

Dentz, Bernard (Department: 1625)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C549S469000, C435S126000, C435S256100

Reexamination Certificate

active

07148254

ABSTRACT:
The present invention relates to 2-phenylbenzofurans of formula (I)which are formed, during fermentation, by the microorganism Aspergillus flavipes ST003878 (DSM 15290), to a process for preparing them and to their use as pharmaceuticals for the treatment and/or prophylaxis of bacterial infectious diseases or mycoses.

REFERENCES:
patent: 6043071 (2000-03-01), DeBouck et al.
patent: 2386891 (2003-10-01), None
patent: 2001-286292 (2001-10-01), None
patent: WO 02/10156 (2002-02-01), None
patent: WO 03/097815 (2003-11-01), None
Barrow et al, Sprioquinazoline, A Novel Substance P Inhibitor With A New Carbon Skeleton, Isolated FromAspergillus flavipes, Journal of Natural Products, vol. 57, No. 4, 1994, pp. 471-476.
Brock et al, Microbial Genetics, Biology of Microorganisms, 7th Edition, Chapter 7, pp 238-247.
Kohno et al, TMC-169, a New Antibiotic of the Aspochalasin Group Produced byAspergillus flavipes, Journal of Antibiotics, vol. 52, No. 6, 1999, pp. 575-577.
March J., Advanced Organic Chemistry, Reactions, Mechanisms, and Structure, Advanced Organic Chemistry, John Wiley & Sons, 4th Edition, 1992.
Raistrick et al, Flavipin, a Crystalline Metabolite ofAspergillus flavipes, Biochem J., Vold. 63, 1956, pp. 395-406.
Raistrick et al, Studies in the Biochemistry of Micro-organisms; Flavipin, A Crystalline Metabolite OfAspergillus flavipes, Dept. of Biochem, London School of Hygiene and Tropical Medicine, Univ. of London, 1956, pp. 395-406.
Ravin, L. J., Preformulation, Remington's Pharmaceutical Sciences, 17, 1985, pp. 1409-1423.
Stolp H., Microbial ecology: organisms, habitata, activities, Cambridge University Press, Cambridge, GB, 1988, p. 180.
Sulzenbacher et al, Crystal Structure ofStreptococcus pneumoniaeN-Acetyl-glucosamine-1-phosphate Uridyltransferase Bound to Acetyl-coenzyme A Reveals a Novel Active Site Architecture, Journal of Biological Chemistry; vol. 276, No. 15, 2001, 11844-11851.

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