2-phenylazulene derivatives and a manufacturing method of these

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...

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514530, 514569, 514570, 514573, 514709, 514886, 514887, 514916, 560 10, 562427, 564 84, 564 89, 568 33, 568 34, A61K 31235, A61K 3119, A61K 31110, A61K 3118

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058439994

ABSTRACT:
A series of new azulene derivatives are disclosed, which are represented by the following formula; ##STR1## wherein: R.sub.1 is hydrogen atom, lower alkoxycarbonyl group, carboxy group, halogen atom, lower alkyl group, phenyl group or lower alkanoyl group; R.sub.2, R.sub.3 and R.sub.4 are hydrogen atom, lower alkyl group, lower alkoxy group or halogen atom; X is lower alkyl group or amino group.
The compounds of the present invention are useful for treatment of inflammation.

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